See More

What is OPSUMIT®?

OPSUMIT® is a prescription medicine used to treat pulmonary arterial hypertension (PAH, WHO Group 1). PAH is high blood pressure in the arteries of your lungs. OPSUMIT® can:

The most important information about OPSUMIT® (macitentan)

Do not take OPSUMIT® if you are pregnant or trying to get pregnant. OPSUMIT® can cause serious birth defects if taken while pregnant.

Women who are able to get pregnant must have negative pregnancy tests:

Contact Us


1-800-Janssen (1-800-526-7736)
Mon-Fri, 8 AM-8 PM ET

If this is an emergency, call 911.

If patients or caregivers have any questions about individual treatment, they should always talk to their healthcare team first.

To report suspected adverse reactions, contact Janssen at 1-800-Janssen (1-800-526-7736), or FDA at 1-800-FDA-1088 or