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What is OPSUMIT®?

OPSUMIT® is a prescription medicine used to treat pulmonary arterial hypertension (PAH, WHO Group 1). PAH is high blood pressure in the arteries of your lungs. OPSUMIT® can:

The most important information about OPSUMIT® (macitentan)

Do not take OPSUMIT® if you are pregnant or trying to get pregnant. OPSUMIT® can cause serious birth defects if taken while pregnant.

Women who are able to get pregnant must have negative pregnancy tests:

How OPSUMIT® Can Help

OPSUMIT® helps open blood vessels between the heart and lungs

When you have PAH, your body may produce too much of a substance called endothelin. This can cause the blood vessels in your lungs to narrow, restricting blood flow and putting strain on the heart. OPSUMIT® targets the endothelin pathway specifically, and works to open these narrow blood vessels.

Find out more about how PAH is treated

Learn about the 3 pathways that PAH treatments target.